Bureau Home Bureau Home About Us Leadership Key Topics Remarks and Releases 2021–2025 Archive HomeBureaus & Offices > Under Secretary for Arms Control and International Security ...Bureau of International Security and Nonproliferation hide Bureau of International Security and Nonproliferation Our Interim Mission The Bureau of International Security and Nonproliferation (ISN) executes the President’s mission of protecting Americans and the America First Policy through a range of strategic programs. ISN works to prevent the proliferation of weapons of mass destruction (WMD), their delivery systems, destabilizing advanced conventional weapons, and related technologies. Additionally, ISN protects and promotes U.S. technological leadership through export controls and expanding the peaceful uses of U.S. nuclear technology. Through implementation of U.S. policies, programs, and agreements, ISN actively shapes the international security environment and addresses malign proliferation challenges to strengthen U.S. leadership on the world stage. Senior Bureau Official, Bureau of International Security and Nonproliferation Paul Watzlavick Follow Us: Twitter Facebook Flickr LinkedIn The Latest March 26, 2025 Commemorating the 50th Anniversary of the Biological Weapons Convention Fifty years ago, the international community took a historic step toward eliminating biological weapons. The entry into force on March 26, 1975, of the Convention on the Prohibition of the Development, Production and Stockpiling of Bacteriological (Biological) and Toxin Weapons and on Their Destruction – commonly referred to as the Biological Weapons Convention (BWC) – attested to the determination […] August 1, 2025 Office of the Historian, Shared Knowledge Services, Bureau of Administration Releases Foreign Relations July 16, 2025 United States and Bahrain Sign Memorandum of Understanding Concerning Strategic Civil Nuclear Cooperation July 16, 2025 Secretary of State Marco Rubio and Bahraini Foreign Minister Dr. Abdullatif bin Rashid Al Zayani at the Signing Ceremony See All Our Priorities Export Controls Policy Multilateral Coordination for Critical Technology Protection Nonproliferation Sanctions Civil Nuclear Energy Initiatives Export Controls Policy The United States uses export controls to protect national security interests and promote our foreign policy objectives. The State Department also employs export controls to prevent state and non-state actors from using goods and technologies to abuse human rights. Learn more about export controls policy Export Controls Policy Multilateral Coordination for Critical Technology Protection ISN coordinates a multilateral network to better protect sensitive technologies, quantum industries, and critical infrastructure from exploitation by national adversaries. ISN facilitates information exchange and gatherings to increase risk awareness, exchange information and best practices, and coordinate efforts to protect sensitive technologies and critical infrastructure. Learn more about Multilateral Coordination for Critical Technology Protection Multilateral Coordination for Critical Technology Protection Nonproliferation Sanctions The United States imposes sanctions under various legal authorities against foreign individuals, private entities, and governments that engage in proliferation activities, including Iran, Syria, and North Korea. Learn more about Nonproliferation Sanctions Nonproliferation Sanctions Civil Nuclear Energy Initiatives ISN develops U.S. policy on peaceful nuclear cooperation to advance U.S. national security priorities and civil nuclear energy initiatives. Civil nuclear energy policies advance U.S. priorities bilaterally and multilaterally through a variety of binding agreements, such as 123 agreements. Learn more about Civil Nuclear Energy Initiatives Civil Nuclear Energy Initiatives Offices Office of Congressional and Public Affairs Office of Conventional Arms Threat Reduction Office of Cooperative Threat Reduction Office of Counterproliferation Initiatives Office of Critical Technology Protection Office of Export Control Cooperation Office of Missile, Biological, and Chemical Nonproliferation Office of Multilateral Nuclear and Security Affairs Office of Nuclear Energy, Safety, and Security Office of Policy Coordination Office of The Biological Policy Staff Office of the Nonproliferation and Disarmament Fund Office of Weapons of Mass Destruction Terrorism
